NIH scientists take totally tubular journey through brain cells

Study may advance understanding of how brain cell tubes are modified under normal and disease conditions

In a new study, scientists at the National Institutes of Health took a molecular-level journey into microtubules, the hollow cylinders inside brain cells that act as skeletons and internal highways. They watched how a protein called tubulin acetyltransferase (TAT) labels the inside of microtubules. The results, published in Cell, answer long-standing questions about how TAT tagging works and offer clues as to why it is important for brain health.

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This page was last updated on Friday, January 21, 2022