NIH recruits five Lasker Clinical Research Scholars
The National Institutes of Health has selected five researchers as new Lasker Clinical Research Scholars as part of a joint initiative with the Albert and Mary Lasker Foundation to foster the next generation of great clinical scientists.
This highly competitive program provides talented, early-stage researchers the opportunity to carry out independent clinical and translational research for five to seven years at the NIH. The researchers also have the possibility of additional years of financial support, at the NIH or an NIH-funded research institution, upon project review.
The scholars are Rebecca Brown, M.D.; Christian Hinrichs, M.D.; Beth Kozel, M.D., Ph.D.; Armin Raznahan, M.D., Ph.D.; and Natalie Shaw, M.D. Kozel was recruited from St. Louis Children's Hospital and Washington University School of Medicine in St. Louis; Shaw was recruited from Massachusetts General Hospital and Harvard Medical School in Boston. The others were recruited from time-limited assistant clinical investigator positions within the NIH. They join five NIH Lasker Scholars hired since 2012.
"NIH hopes to serve as a catalyst for a national effort to nurture clinician-scientists by providing these talented scholars with the opportunities and protected research time they need to thrive," said NIH Director Francis S. Collins, M.D., Ph.D. "With 10 total scholars, it's thrilling to see the Lasker Scholar Program vision taking flight."
Brown works in the Diabetes, Endocrinology, and Obesity Branch of the National Institute of Diabetes and Digestive and Kidney Diseases. Her laboratory studies extreme insulin resistance as well as the role of leptin, the "satiety hormone," on metabolism and weight gain. By studying rare diseases of insulin and leptin regulation, Brown hopes to provide insights and ultimately treatments for common conditions such as obesity and the metabolic syndrome.
Hinrichs works in the Experimental Transplantation and Immunology Branch of the Center for Cancer Research in the National Cancer Institute. He researches immunotherapy for HPV+ cancers including cervical, oropharyngeal, anal, vulvar, vaginal, and penile malignancies. Hinrichs laboratory has discovered personalized T cell and gene therapies for HPV+ cancers. As a Lasker Scholar, he will be developing these treatments in clinical trials, investigating why they work in some patients and not in others, and working to discover additional new treatments.
Kozel is a geneticist and a matrix and vascular biologist at the National Heart, Lung, and Blood Institute. She seeks to better understand the factors that influence vascular disease severity in patients with rare connective tissue disorders. The majority of her work is focused on the study of two elastin insufficiency-related diseases: Williams syndrome, a neurodevelopmental condition, and isolated supravalvular aortic stenosis.
Raznahan leads the Developmental Neurogenomics Unit in the Child Psychiatry Branch of the National Institute of Mental Health. He combines neuroimaging and genomic and systems-biology approaches to map human brain development and genetically-defined disorders that increase risk for neuropsychiatric impairment. This work aims to identify sets of genes and brain systems that can account for the emergence of a shared behavioral syndrome (e.g., autism) across distinct genetic disorders.
Shaw conducts research in the Clinical Research Branch at the National Institute of Environmental Health Sciences and is also an adjunct faculty member at the University of North Carolina at Chapel Hill School of Medicine. She is interested in the environmental and genetic control of pubertal development and, specifically, in the effect of sleep disruption and obesity on reproductive hormone secretion. As a Lasker Scholar, Shaw's work will focus on the genetics behind the timing of pubertal development in adolescent girls.
Lasker Scholars have access to the NIH Clinical Center, the largest hospital in the world devoted to clinical research. The Lasker Foundation will provide additional developmental support to the scholars while they are working at NIH by funding travel to scientific meetings and providing the opportunity to participate in selected foundation activities, including the Lasker Award ceremonies. Learn more about the program at https://www.nih.gov/science/laskerscholar.
This page was last updated on Friday, January 21, 2022