NIEHS Scientists Identify the Immunity Proteins That Cause a Majority of DNA Damage in Several Types of Human Cancers

Monday, August 10, 2015

New research published online August 10 in the journal Nature Genetics found that a mutation-causing enzyme known as APOBEC3A (A3A) may be the main cause of mutations in certain cancers. Previous work from other groups implicated another APOBEC enzyme, known as APOBEC3B (A3B).