Genetic mystery of Behcet's disease unfolds along the ancient Silk Road

NIH researchers identify new gene variants associated with risk for complex inflammatory syndrome

Researchers have identified four new regions on the human genome associated with Behcet's disease, a painful and potentially dangerous condition found predominantly in people with ancestors along the Silk Road. For nearly 2,000 years, traders used this 4,000-mile network linking the Far East with Europe to exchange goods, culture and, in the case of the Silk Road disease, genes. National Institutes of Health researchers and their Turkish and Japanese collaborators published their findings in the Jan. 6, 2013, advance online issue of Nature Genetics.

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This page was last updated on Friday, January 21, 2022