Crystal clear images uncover secrets of hormone receptors

NIH researchers gain better understanding of how neuropeptide hormones trigger chemical reactions in cells

Many hormones and neurotransmitters work by binding to receptors on a cell’s exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level images to show how the neuropeptide hormone neurotensin might activate its receptors. Their description is the first of its kind for a neuropeptide-binding G protein-coupled receptor (GPCR), a class of receptors involved in a wide range of disorders and the target of many drugs.

Crystal clear images uncover secrets of hormone receptors

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This page was last updated on Friday, January 21, 2022