Circuit Tweak Boosts Social Memory in Mice

Thursday, January 7, 2016

NIMH researchers have boosted the staying power of a social memory at least 80-fold by stimulating a circuit they discovered in mouse brain. A male mouse that would normally forget a female mouse it had just met within an hour instead remembered it at least a week later! Researchers precisely tweaked the circuit by genetically priming it to respond to pulses of light –a cutting edge technique called optogenetics. The study is the first to enhance social memory by stimulating a specific circuit.