NIH Director's Seminar Series: Human B cells in health and disease
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B cells contribute to the immune system through two major cellular compartments: long-lived plasma cells that produce protective antibodies and memory B cells that can respond rapidly to pathogens upon re-encounter. However, B cells are highly varied and can become dysregulated and ineffective or even cause disease in certain settings such as chronic infections, autoimmunity, or immune deficiencies. In this lecture, part of the NIH Director's Seminar Series, IRP senior investigator Susan Moir, Ph.D., will discuss how B cells respond to different viral pathogens, namely HIV and SARS-CoV-2, and how differences in the responses to each pathogen can advance our understanding of humoral immunity and help identify correlates of protective immunity following infection or vaccination.
This page was last updated on Monday, October 24, 2022