Experimental agent briefly eases depression rapidly in test

Works in brain like ketamine, with fewer side effects – NIH trial

A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, in a clinical trial conducted by the National Institutes of Health. The experimental agent, called AZD6765, acts through the brain's glutamate chemical messenger system.

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This page was last updated on Friday, January 21, 2022