hippocampus

Neuroimaging Study Supports Two-Stage Theory of Recall

Results Suggest Dual Functions for Memory-Related Brain Area

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Scientists studying memory have been closely scrutinizing a brain structure called the hippocampus ever since a man named Henry Molaison — better known as ‘patient H.M.’ — lost his ability to create new memories after surgeons removed that portion of his brain as a last-ditch treatment for his unrelenting epileptic seizures. For the most part, that research has treated the hippocampus as one homogenous structure. However, a recent IRP study lends support to the growing recognition that recall is a multi-stage process in which different parts of the hippocampus play different roles.

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“Here is an image that is historical because it represents the era (1980s and 1990s) when drug receptors were first being localized in the brain," writes Miles Herkenham, Ph.D.

Herkenham Cannabinoid receptor hippocampus