Gisela T. Storz, Ph.D.
Section on Environmental Gene Regulation
Building 18, Room 113
9000 Rockville Pike
Bethesda, MD 20892
Currently, we have two main interests: the identification and characterization of small noncoding RNAs and the identification and characterization of small proteins of less than 50 amino acids. For two reasons, small RNAs and small proteins have been overlooked. First, biochemical assays do not detect these small molecules. Second, genome annotation misses the corresponding genes, which are poor targets for genetic approaches. However, mounting evidence suggests that both classes of these small molecules play important regulatory roles.
Opdyke JA, Fozo EM, Hemm MR, Storz G. RNase III participates in GadY-dependent cleavage of the gadX-gadW mRNA. J Mol Biol. 2011;406(1):29-43.
Beisel CL, Storz G. The base-pairing RNA spot 42 participates in a multioutput feedforward loop to help enact catabolite repression in Escherichia coli. Mol Cell. 2011;41(3):286-97.
Storz G, Vogel J, Wassarman KM. Regulation by small RNAs in bacteria: expanding frontiers. Mol Cell. 2011;43(6):880-91.
Hobbs EC, Fontaine F, Yin X, Storz G. An expanding universe of small proteins. Curr Opin Microbiol. 2011;14(2):167-73.
Fontaine F, Fuchs RT, Storz G. Membrane localization of small proteins in Escherichia coli. J Biol Chem. 2011;286(37):32464-74.