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The National Institutes of Health (NIH) campuses host a variety of events that inform, challenge, and unite the biomedical research community. IRP investigators lead or participate in many of these events, and they regularly present their work at scientific conferences at the NIH and around the world. We invite you to learn about (and possibly join us in) some of our upcoming events:

Friday, February 27, 2015, 8:30 am to 5:00 pm

Masur Auditorium, NIH Clinical Center (Bldg 10)

The National Institutes of Health (NIH) will celebrate the eighth annual Rare Disease Day with a day-long celebration and recognition of the various rare diseases research activities supported by the NCATS' Office of Rare Diseases Research, the NIH Clinical Center, and other NIH Institutes and Centers; the Food and Drug Administration’s (FDA) Office of Orphan Product Development; other Federal Government agencies; the National Organization for Rare Disorders; the Genetic Alliance; Global Genes; and Uplifting Athletes. Attendance is free and open to the public.

Rare Disease Day at NIH is appropriate for patients and patient advocates, health care providers, researchers, industry representatives, and government employees. We will have talks from academic and government scientists, industry representatives, and the lay community.

In addition to the various scheduled talks (see agenda), posters and exhibits from many groups relevant to the rare diseases research community will be displayed. In association with Global Genes, we again encourage all attendees to wear their favorite pair of jeans.

The Rare Disease Day 2015 event will also be webcast and Clinical Center tours will be available for in-person attendees.

Tuesday, March 3, 2015, 12:00 pm to 1:00 pm

Building 35A Room 640 (ground floor)

The Proteostasis (Protein Homeostasis) Scientific Interest Group (PSIG) will present a seminar entitled "HSP90, Proteostasis and Cancer" by Dr. Len Neckers of the National Cancer Insitute. Dr. Neckers identified the molecular chaperone HSP90 as a key non-oncogene addiction of cancer, demonstrated that HSP90 is an anticancer target, and showed that this target is druggable. Dr. Neckers discovered the first inhibitor of HSP90, geldanamycin, as well as the first-in-human HSP90 inhibitor, 17-AAG. His basic and translational research efforts have facilitated the development of a new class of anticancer drugs. Recently, Dr. Neckers has uncovered a fundamental role for the mitochondrial HSP90 homolog TRAP1 as a key regulator of the balance between oxidative phosphorylation and aerobic glycolysis in cancer cells, expanding our understanding of the Warburg effect in cancer.

This seminar is part of the PSIG bi-monthly seminar series by NIH intramural investigators and occasional extramural guests working on different areas of proteostasis. The seminar is open to all those interested in proteostasis and its universal role in human health and disease. PSIG provides a forum to facilitate communication, and collaboration among NIH intramural and outside researchers who are working on different aspects of the Proteostasis Network. For more information about the PSIG, contact Dr. Andras Orosz at; check the Web site at; or join the LISTSERV at

Friday, March 13, 2015, 8:30 am to 5:00 pm

Porter Neuroscience Building (Building 35A), Room 620/630

The NIH is observing Pi Day one day early, on Friday, March 13, with a half-day event of talks and activities celebrating the intersection between the quantitative and biomedical sciences. Pi Day is an annual celebration of the irregular number pi, 3.14..., on March 14. This year is extra special, with the day 3/14/15 corresponding to 3.1415. (You likely weren’t around in 1592.)

Events include “PiCo” lightning talks and networking event (8:30 to 10:00 a.m.); poster session (10:00 to 11:00); and the inaugural Data Science Lecture, given by Dr. Eric Lander, director of the Broad Institute of MIT and Harvard (11:00 a.m.). The “Workshop on Reproducibility of Data Collection and Analysis” follows. See description and more information on Pi Day at