The National Institutes of Health (NIH) campuses host a variety of events that inform, challenge, and unite the biomedical research community. IRP investigators lead or participate in many of these events, and they regularly present their work at scientific conferences at the NIH and around the world. We invite you to learn about (and possibly join us in) some of our upcoming events. Unless otherwise noted, times listed are Eastern Standard Time (EST).
Friday, July 31, 2015, 11:30 am to 1:00 pm
Lipsett Amphitheater, NIH Clinical Center (Bldg 10)
This year’s AAAS Wachtel Cancer Research Award and Lecture is titled “Cancer evolution and diversity with single cell sequencing" by Nicholas E. Navin, Ph.D., of the MD Anderson Cancer Center. The Wachtel Cancer Research Award is presented to early-career cancer researchers who have made outstanding contributions to the cancer field.
From the speaker: “My goal is to understand genome evolution in human cancers. As tumors evolve from a single cell, they acquire complex somatic mutations and diverge to form distinct lineages and subpopulations. This intratumor heterogeneity confounds basic research and clinical diagnosis, because tools do not exist to resolve it. To address this problem, we developed a single-cell sequencing method to profile genomic copy number in individual tumor cells (Nature 472:90-4, 2011). I used this method to profile hundreds of single cells in two breast cancer patients to delineate clonal diversity and infer patterns of genome evolution. The data revealed multiple clonal subpopulations that shared a common evolutionary lineage. In contrast to the gradual models of tumor progression, the data suggest that these breast tumors grew by punctuated clonal expansions, in which hundreds of genomic rearrangements were acquired in short bursts of evolution. We have also recently developed a powerful new method to perform whole-genome sequencing on single tumor cells. This will enable us to study the evolution of many different classes of somatic mutations (point mutations, indels and structural variants) at base-pair resolution in single cells. In addition to single cell sequencing, my laboratory also uses many genomic and cytological methods to study how cancer genomes evolve. We are also actively developing new computational methods to quantify tumor heterogeneity and understand if these measures correlate with clinical parameters such as survival and resistance to chemotherapy. One method developed is called Ploidy-Seq to deep-sequence intratumor subpopulations and infer mutational chronology and ancestral tumor genomes.”
Thursday, August 13, 2015 to Friday, August 14, 2015
The 2015 Big Data Workshop is titled "Exploring Opportunities for Radiation Oncology in the Era of Big Data." The National Cancer Institute (NCI), American Society for Radiation Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM) are co-sponsoring this two-day workshop for radiation oncology physicians and physicists focused on opportunities for radiation oncology in the era of big data.
The workshop will provide a platform for leaders in big data projects to interact with their peers in radiation oncology research, quality assessment and clinical care. Presentations will include current big data cancer registries, safety and incident reporting systems, and other strategies that will have the greatest impact on radiation oncology research, quality assurance, safety and outcomes analysis/CRE. Abstract submissions will be solicited for poster presentations. See https://www.astro.org/Meetings-and-Events/2015-Big-Data-Workshop/Index.aspx for registration and more details.
Tuesday, September 1, 2015 to Thursday, September 3, 2015
Natcher Conference Center
Following the sell-out 2014 conference, we are pleased to announce a third Preventing Overdiagnosis conference, sponsored by the National Cancer Institute. Refer to http://www.preventingoverdiagnosis.net for the agenda and registration.
Although hard to believe, there’s growing scientific evidence suggesting many people are overdiagnosed across a lot of different conditions, including asthma, breast cancer, and high blood pressure, and you can read more in the books and articles on our readings page. One common way overdiagnosis can happen is when healthy people who attend screening programs or receive tests during check-ups are diagnosed and subsequently treated for the early form of a disease which would never in fact have harmed them. With breast cancer screening for example, a recent systematic review of studies published in the British Medical Journal suggests that up to one in three of the cancers detected via screening may be overdiagnosed. There are similar concerns with overdiagnosis of prostate, thyroid and kidney cancers.
Wednesday, September 2, 2015, 3:00 pm to 4:00 pm (reception to follow)
Masur Auditorium, NIH Clinical Center (Bldg 10)
Edward Boyden, Ph.D., Associate Professor of Media Arts and Sciences, MIT, presents "Tools for Comprehensive Molecular Imaging and Dynamical Control of Biological Systems" as both the first of 3 NIH Director's Lectures and the first lecture of the 2015-2016 season of the Wednesday Afternoon Lecture Series (WALS).
The 2015–2016 WALS season starts with a bang. The first NIH Director’s Lecture (1 of 3 each season) is with Ed Boyden, the celebrated neuroscientist at MIT who, with Karl Deisseroth, greatly advanced the field of optogenetics. In 2010, his work was recognized as the “Method of the Year” by the journal Nature Methods. More recently he shared the 2013 Grete Lundbeck European Brain Research Prize for outstanding contributions to European neuroscience–the largest neuroscience prize in the world. In 2008, at age 29, he was named to Discover magazine's 'Top 20 Under 40' list. Boyden leads the MIT Media Lab’s Synthetic Neurobiology research group, which develops tools for mapping, controlling, observing, and building dynamic circuits of the brain, and uses these neurotechnologies to understand how cognition and emotion arise from brain network operation, as well as to enable systematic repair of intractable brain disorders such as epilepsy, Parkinson's disease, and post-traumatic stress disorder. His research group has invented a suite of optogenetic tools that are now in use by thousands of research groups around the world for activating and silencing neurons with light.
Come join your colleagues, DDIR Michael Gottesman and NIH Director Francis Collins at these top-notch lectures, even if you think they are outside of your area of interest. The Wednesday Afternoon Lecture Series is this highest-profile scientific lecture series at the NIH, created to keep the NIH community informed of the latest world-class science. Speakers are nominated by NIH scientific staff. Receptions with the speaker follow each lecture. The 2015–2016 schedule will be posted by late summer at http://oir.nih.gov/wals.
Thursday, September 10, 2015 to Friday, September 11, 2015
Fishers Lane Auditorium, Rockville, Md.
Please join us for an NIH symposium titled “Linking Disease Model Phenotypes to Human Conditions.” The purpose of the meeting is to convene a colloquium on the current status of phenomics and its role in closing the gap that exists between biomedical research and clinical medical practice. The wealth of whole organism, cellular, and molecular data generated in the research laboratory must be translated into clinically relevant knowledge that enables the physician to make the best possible treatment decisions. Phenomics is gaining momentum due to the availability of the complete genomes for many organisms as well as higher throughput methods to genetically modify model organism genomes and observe and record phenotypes. Disease models comprise some of the most important tools of biomedical research. The efficacy of the use of disease models is based upon the principles of evolutionary conservation between species, including conservation of pathogenic disease mechanisms. The lack of alignment of phenotypes between model species and humans has been a historic impediment to understanding disease processes. Further progress depends upon integration of clinical, biological and genomic data and development of the tools for identification and analysis of specific and amendable disease-causing molecular phenotypes of various diseases. This symposium is sponsored by the Division of Comparative Medicine at ORIP/DPCPSI/OD/NIH.
If interested, please refer to the symposium program and registration to attend this event at http://www.scgcorp.com/linkingdisease2015/. We plan to accommodate 50 NIH attendees at the Symposium. Once these 50 spaces are filled, additional NIH employees, who are registered, will be placed on a waiting list and will be notified, if space becomes available. Please register early; space is limited. For more information on meeting logistics and registration, contact Mark A. Dennis at firstname.lastname@example.org or Oleg Mirochnitchenko at Oleg.Mirochnitchenko@nih.gov.
Wednesday, September 16, 2015 to Friday, September 18, 2015
The 2015 NIH Research Festival: A Celebration of Intramural Science will be different from previous years', as our goal is to kick-off the scientific initiatives outlined in the Intramural long-term plan, now endorsed by the Advisory Committee to the Director. We strongly encourage you, as a member of the NIH Intramural Research Program (IRP), to participate in this year’s Festival by both attending the scientific sessions and presenting your own work to your fellow IRP scientists.
To submit an abstract for inclusion in one of the poster sessions, simply point your Web browser to the poster abstract submission site, at http://researchfestival.nih.gov/forms/poster.cgi. Each individual is limited to a single poster as a first author in order to allow as many people to present their work. The poster-abstract submission period closes at 11:59 p.m. on Monday, June 29. You will be able to make changes to your abstract submission up until that time, after which all submissions will be locked. All poster submissions will then be reviewed and accepted poster applicants will be notified by e-mail this summer. For those of you presenting work that could be construed as a public disclosure of a new invention, please consult with your IC's technology transfer office (http://www.ott.nih.gov/technology-development-coordinators) about filing a patent application prior to submitting your abstract. If you have any questions regarding poster submissions (or any aspect of the Research Festival), please contact Jacqueline Roberts, the Research Festival Coordinator, at email@example.com. For information on last year's Research Festival, visit http://researchfestival.nih.gov.
Tuesday, September 22, 2015 to Wednesday, September 23, 2015
Bldg 35 Auditorium (620/630)
Join us for the third NCI-Pancreatic Cancer Symposium, “Current Advances and Future Challenges in Research and Treatment." Pancreatic cancer remains one of the most lethal malignancies and is expected to be the second leading cause of death due to cancer by 2020 in the United States. Recent progress in the basic and clinical research has identified molecular targets that could be harnessed in improving survival in patients with pancreatic cancer. This symposium presents recent advances in our understanding of the development, progression, early detection and treatment of pancreatic cancer, and will provide an exciting forum to discuss the challenges in improving diagnosis, prevention and disease outcome. See http://ncifrederick.cancer.gov/events/PancreaticCancer2015/ for list of speakers and other information. Deadline for submission of abstracts is August 10. Registration is free but seating is limited, so please register online.
Tuesday, September 29, 2015 to Wednesday, September 30, 2015
Natcher Conference Center (Building 45)
Mark your calendars and plan to attend the sixth NHLBI Symposium on Cardiovascular Regenerative Medicine. The event will bring together experts in stem cell biology, cardiovascular development, translating stem cell biology, cardiac remodelling and inflammation, vascular remodelling and inflammation, and tissue engineering/genome editing/new technologies. The emphasis will be on recent discoveries and trends. We will examine the challenges and critical questions that require answers as the field moves forward to clinical applications. The Symposium’s goals are to help the science and field move forward, to find consensus regarding the translation of stem cell biology and research into a clinical setting, and to inspire participants in their own work. More information is available on the symposium's website. Abstract submission deadline is July 1.
Tuesday, October 13, 2015
Natcher Conference Center (Bldg 45)
Join us for the National Institute of Nursing Research’s (NINR) 30th Anniversary Scientific Symposium and Poster Session, “Advancing Science, Improving Lives." This special event marks the beginning of a yearlong observation of the Institute’s first 30 years at the NIH. The symposium comprises keynote addresses, scientific presentations, a scientific panel discussion, and a research poster session. It will highlight many of the accomplishments of NINR and its scientists and showcase the positive impact that our science has had on the lives of millions of Americans. This event is free of charge, but registration is required. For more information and to register for the event, please visit http://www.ninr.nih.gov/30years. Note that NINR’s call for abstracts for a poster session is now closed.
Friday, October 23, 2015, 10:00 am
Masur Auditorium, NIH Clinical Center (Bldg 10)
The Office of Intramural Research, Office of the Director, NIH, invites you to the tenth annual Philip S. Chen, Jr., Ph.D., Distinguished Lecture on Innovation and Technology Transfer. Robert Kotin will present “Unexpected Results from Unconventional Approaches to Adeno-associated Virus Research.” Kotin was Senior Investigator (1999–2014) at the National Heart, Lung and Blood Institute and is currently Vice President of Voyager Therapeutics and Adjunct Professor at the Gene Therapy Center of the University of Massachusetts Medical School in Worcester.