Robert Geoffrey Nelson, M.D., Ph.D.
Senior Investigator
Chronic Kidney Disease Section, Phoenix Epidemiology and Clinical Research Branch
NIDDK
Building PECRB, Room 604
1550 E Indian School Rd
Phoenix, AZ 85014
+1 602 200 5205
Research Topics
Diabetes is the leading cause of kidney disease worldwide and is a major cause of death and disability. Our research goal is to find the causes and identify new and effective treatments to slow the progression or prevent the development of diabetic kidney disease.
Current Research
Our lab has worked with the Pima Indians in Arizona since 1986, focusing primarily on the kidney complications of type 2 diabetes mellitus. Current activities include identifying biomarkers and underlying mechanisms for diabetic kidney disease and characterizing the structural and functional changes within the kidneys that occur with the development and progression of diabetic kidney disease. Gene expression in kidney tissue and epigenetic modification of gene expression is also a major focus of our work.
Biography
- Ph.D., University of California, Los Angeles, 1998
- M.P.H., Harvard University, 1986
- B.S., M.D., Loma Linda University, 1978
Selected Publications
Inker LA, Eneanya ND, Coresh J, Tighiouart H, Wang D, Sang Y, Crews DC, Doria A, Estrella MM, Froissart M, Grams ME, Greene T, Grubb A, Gudnason V, Gutiérrez OM, Kalil R, Karger AB, Mauer M, Navis G, Nelson RG, Poggio ED, Rodby R, Rossing P, Rule AD, Selvin E, Seegmiller JC, Shlipak MG, Torres VE, Yang W, Ballew SH, Couture SJ, Powe NR, Levey AS, Chronic Kidney Disease Epidemiology Collaboration.. New Creatinine- and Cystatin C-Based Equations to Estimate GFR without Race. N Engl J Med. 2021.
Nelson RG, Knowler WC, Kretzler M, Lemley KV, Looker HC, Mauer M, Mitch WE, Najafian B, Bennett PH. Pima Indian Contributions to Our Understanding of Diabetic Kidney Disease. Diabetes. 2021;70(8):1603-1616.
Satake E, Saulnier PJ, Kobayashi H, Gupta MK, Looker HC, Wilson JM, Md Dom ZI, Ihara K, O'Neil K, Krolewski B, Pipino C, Pavkov ME, Nair V, Bitzer M, Niewczas MA, Kretzler M, Mauer M, Doria A, Najafian B, Kulkarni RN, Duffin KL, Pezzolesi MG, Kahn CR, Nelson RG, Krolewski AS. Comprehensive Search for Novel Circulating miRNAs and Axon Guidance Pathway Proteins Associated with Risk of ESKD in Diabetes. J Am Soc Nephrol. 2021;32(9):2331-2351.
Menon R, Otto EA, Sealfon R, Nair V, Wong AK, Theesfeld CL, Chen X, Wang Y, Boppana AS, Luo J, Yang Y, Kasson PM, Schaub JA, Berthier CC, Eddy S, Lienczewski CC, Godfrey B, Dagenais SL, Sohaney R, Hartman J, Fermin D, Subramanian L, Looker HC, Harder JL, Mariani LH, Hodgin JB, Sexton JZ, Wobus CE, Naik AS, Nelson RG, Troyanskaya OG, Kretzler M. SARS-CoV-2 receptor networks in diabetic and COVID-19-associated kidney disease. Kidney Int. 2020;98(6):1502-1518.
Nelson RG, Grams ME, Ballew SH, Sang Y, Azizi F, Chadban SJ, Chaker L, Dunning SC, Fox C, Hirakawa Y, Iseki K, Ix J, Jafar TH, Köttgen A, Naimark DMJ, Ohkubo T, Prescott GJ, Rebholz CM, Sabanayagam C, Sairenchi T, Schöttker B, Shibagaki Y, Tonelli M, Zhang L, Gansevoort RT, Matsushita K, Woodward M, Coresh J, Shalev V, CKD Prognosis Consortium.. Development of Risk Prediction Equations for Incident Chronic Kidney Disease. JAMA. 2019;322(21):2104-2114.
Related Scientific Focus Areas
This page was last updated on April 29th, 2022