Richard S. Chadwick, Ph.D.

Senior Investigator

Section on Auditory Mechanics

NIDCD

Building 10, Room 5D/49
10 Center Drive
Bethesda, MD 20892

301-435-1957

chadwick@helix.nih.gov

Research Topics

The aim of the section on Auditory Mechanics is to increase knowledge of the hearing process via an interweaving of mathematical, physical, and biological approaches and techniques. Advanced modeling techniques are used interactively with biophysical and structural data obtained from tissues in the organ of Corti to study cochlear physical phenomena related to the transduction of sound to auditory nerve impulses. Special emphasis is directed toward developing techniques to integrate subcellular, cellular, and macroscopic interactions.

Selected Publications

  1. Logue JS, Cartagena-Rivera AX, Baird MA, Davidson MW, Chadwick RS, Waterman CM. Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration. Elife. 2015;4:e08314.

  2. Manoussaki D, Shin WD, Waterman CM, Chadwick RS. Cytosolic pressure provides a propulsive force comparable to actin polymerization during lamellipod protrusion. Sci Rep. 2015;5:12314.

  3. Cartagena-Rivera AX, Van Itallie CM, Anderson JM, Chadwick RS. Apical surface supracellular mechanical properties in polarized epithelium using noninvasive acoustic force spectroscopy. Nat Commun. 2017;8(1):1030.

  4. Gavara N, Chadwick RS. Noncontact microrheology at acoustic frequencies using frequency-modulated atomic force microscopy. Nat Methods. 2010;7(8):650-4.

  5. Gavara N, Chadwick RS. Determination of the elastic moduli of thin samples and adherent cells using conical atomic force microscope tips. Nat Nanotechnol. 2012;7(11):733-6.


This page was last updated on September 7th, 2018