Ilias Alevizos, D.M.D., M.M.Sc.


Molecular Physiology and Therapeutics Branch/Sjögren's Syndrome Clinic


Building 10, Room 1N110
10 Center Drive
Bethesda, MD 20892


Research Topics

  • Mechanisms of salivary gland secretion
  • Role of Regulatory RNAs in function
  • Gene therapy
  • Genomics
  • Oral disease biomarkers


Dr. Ilias Alevizos received his B.S. in biology from Adelphi University, his D.M.D. from Tufts University, his MMSc. from Harvard University, and specialized in oral and maxillofacial pathology at Harvard University. He has completed postdoctoral research appointments at MIT and University of Padova, Italy, and a clinical research fellowship at NIH. During his postdoctoral appointments he focused on the exploration of high throughput genomics for disease development of genetic signatures that would allow for the identification of early cellular changes that can serve as biomarkers or pharmacologic targets. Dr. Alevizos is a member of the multidisciplinary Sjogren's syndrome medical team at NIH. He possesses extensive clinical experience in the diagnosis and management of oral diseases, especially ones related to salivary glands. He is currently participating in many clinical research protocols at NIH. His basic science focus is on salivary gland physiology, and more specifically on how alterations in the expression of non-coding genes participate in the development of diseases impairing the function of salivary glands.

Selected Publications

  1. Alevizos I, Alexander S, Turner RJ, Illei GG. MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome. Arthritis Rheum. 2011;63(2):535-44.

  2. Alevizos I, Illei GG. MicroRNAs as biomarkers in rheumatic diseases. Nat Rev Rheumatol. 2010;6(7):391-8.

  3. Baum BJ, Alevizos I, Zheng C, Cotrim AP, Liu S, McCullagh L, Goldsmith CM, Burbelo PD, Citrin DE, Mitchell JB, Nottingham LK, Rudy SF, Van Waes C, Whatley MA, Brahim JS, Chiorini JA, Danielides S, Turner RJ, Patronas NJ, Chen CC, Nikolov NP, Illei GG. Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction. Proc Natl Acad Sci U S A. 2012;109(47):19403-7.

  4. Jang SI, Ong HL, Gallo A, Liu X, Illei G, Alevizos I. Establishment of functional acinar-like cultures from human salivary glands. J Dent Res. 2015;94(2):304-11.

  5. Michael A, Bajracharya SD, Yuen PS, Zhou H, Star RA, Illei GG, Alevizos I. Exosomes from human saliva as a source of microRNA biomarkers. Oral Dis. 2010;16(1):34-8.

This page was last updated on June 12th, 2012