The NIH is composed of 27 Institutes and Centers. Each Institute or Center has its own specific research agenda and administrates its own budget. All but three receive their funding directly from Congress. The NIH Intramural Research Program (IRP) comprises intramural programs embedded in 24 of the NIH Institutes and Centers and located on one or more of the NIH campuses.
Learn more about the IRP components and their individual mandates by clicking on the links below.
Center for Cancer Research (CCR)
CCR conducts basic and clinical cancer research and develops novel therapeutic interventions for cancer and HIV patients.
Division of Cancer Epidemiology and Genetics (DCEG)
DCEG conducts population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention.
NEI carries out basic and clinical research to develop therapeutic interventions for the prevention and treatment of visual system diseases.
NHLBI performs scientific and clinical research to better understand the biology and clinical pathology of heart, lung, and blood diseases.
NHGRI conducts laboratory, clinical, and behavioral research focused on human genetic disease and develops methods for the detection, prevention, and treatment of genetic disorders.
NIA provides an academic setting for a comprehensive effort to understand aging through multidisciplinary investigator-initiated research.
NIAAA aims to identify the causes and consequences of alcoholism and excessive drinking, and to understand the underlying biological processes of disease.
Division of Intramural Research
NIAID conducts basic and clinical research related to immunology, allergy, and infectious diseases to promote the development of new vaccines, therapeutics, and diagnostics.
Vaccine Research Center (VRC)
The VRC’s mission is to conduct research that facilitates the development of effective vaccines for human disease, with a focus on AIDS.
NIAMS focuses on studying diseases that involve bones, joints, muscles, and skin through clinical and laboratory research.
NIBIB integrates engineering and physical sciences with the life sciences to advance basic research and medical care with biomedical technologies.
NICHD focuses its research on the biology of human development and reproduction to ensure the birth of healthy babies and the health of infants and children into adulthood.
NIDCD conducts basic and clinical research in the areas of human communication.
NIDCR conducts basic laboratory, translational, and clinical research in support of craniofacial and dental health using the latest techniques in biomedical science.
NIDDK conducts research related to metabolic, digestive, kidney, and hematologic diseases and diabetes mellitus.
NIDA conducts state-of-the-art research on basic mechanisms that underlie drug abuse and addiction, and develops new methods of treatment.
The NIEHS aims to reduce the burden of human illness and disability by understanding how the environment influences the development and progression of human disease.
NIMH researches the mechanisms of normal brain function at the behavioral, systems, and molecular levels, and conducts clinical investigations of mental illness.
NIMHD conducts research on differences in the incidence, prevalence, mortality, and burden of diseases and other adverse health conditions that exist among specific population groups.
NINDS conducts basic, translational, and clinical research aimed at relieving the burden of neurological disorders and stroke.
NINR seeks to understand the underlying biological mechanisms of a range of symptoms, their effect on patients, and how patients respond to interventions.
National Center for Biotechnology Information (NCBI)
NCBI creates and maintains databases for the medical and scientific communities and general public, including literature, molecular, and genomic databases.
Lister Hill National Center for Biomedical Communications (LHNCBC)
The Lister Hill Center conducts and supports research and development with the goal of improving access to high quality biomedical information for individuals around the world.
CIT develops leading-edge computational methods and tools to solve complex biomedical laboratory and clinical research problems.
NCCIH conducts basic, clinical, and translational research focusing on the role of the brain in perceiving, modifying, and managing pain.
NCATS leads scientific programs and projects designed to advance new technologies that make the preclinical phase and early clinical phases of translation more predictive and efficient
The Clinical Center is the nation’s largest hospital devoted entirely to leading-edge clinical biomedical research.